WHAT IS ABACUS?

ABaCUS is a no-frills program developed to investigate the significance of
the putative correspondence between exons and units of protein structure.
This type of analysis takes the form of an attempt to eliminate the
reference hypothesis (sometimes called a "null" hypothesis) that no
correspondence exists.  A reference hypothesis in this case consists of a
reference model for random gene structures, and a scoring rule for
quantifying correspondences.

ABaCUS creates and reads files containing observed data supplied by the
user, then uses this information to generate reference genes according to
one of several available models.  The observed and reference genes are then
scored according to a correspondence rule designated by the user, and the
scores are compared in order to determine whether the reference hypothesis
(i.e., no correspondence) can be rejected.

This program may be useful in your research if you are studying the origin
and evolution of intron-containing genes.

This is the porting for AMIGA, and has been compiled with SAS-C V6.51.
To run simply open a SHELL and type ABACUS, for infos on using ABACUS
read the manual ABACUS.HLP. This archive includes also a PDB file for
a tutorial: a cytochrome C from rice embryos (read the manual).

Thanx to

 Dr. Arlin Stoltzfus and Dr. David Spencer
 Canadian Institute for Advanced Research, Dalhousie University

for this excellent tool.

 Steve Peruzzi
 peru@maya.dei.unipd.it
 University of Padua, ITALY
                         

 PERMSSN    UID  GID    PACKED    SIZE  RATIO     CRC       STAMP          NAME
---------- ----------- ------- ------- ------ ---------- ------------ -------------
[generic]                  548    1188  46.1% -lh5- a52b Mar  6  1995 ABaCUS.info
[generic]                38346   75028  51.1% -lh5- dd81 Mar  6  1995 ABaCUS/abacus
[generic]                28535   75587  37.8% -lh5- bff5 Mar  6  1995 ABaCUS/abacus.hlp
[generic]                  748    4653  16.1% -lh5- e5a8 Mar  6  1995 ABaCUS/abacus.hlp.info
[generic]                  599    1755  34.1% -lh5- afee Mar  6  1995 ABaCUS/abacus.info
[generic]                20826   77635  26.8% -lh5- 110e Mar  6  1995 ABaCUS/pdb1ccrs.txt
[generic]                 1011    1816  55.7% -lh5- 6e60 Mar  6  1995 ABaCUS/pdb1ccrs.txt.info
[generic]                  849    1665  51.0% -lh5- 11cb Mar  6  1995 ABaCUS/readme.txt
[generic]                 1011    1816  55.7% -lh5- 3c01 Mar  6  1995 ABaCUS/readme.txt.info
---------- ----------- ------- ------- ------ ---------- ------------ -------------
 Total         9 files   92473  241143  38.3%            Mar  7  1995